The goal of the Cancer Mechanisms (CM) program is to catalyze basic research pertinent to cancer-relevant mechanistic discovery to generate new knowledge leading to enhanced diagnosis, treatment, and prevention of primary cancer and systemic recurrence of cancers highly represented in the TCI immediate catchment area. CM is dedicated to exceptional basic research concentrating on the tumor microenvironment (TME), cell signaling pathways, and epigenetic and transcriptional control in cancer.
Specific Aims:
1. Investigate cellular interactions within the tumor microenvironment.
2. Elucidate cell signaling networks in cancer.
3. Investigate epigenetics and gene regulation of tumor biology