Investigators in our laboratories at the Department of Psychiatry are conducting ground-breaking research, often in collaboration with other departments and focusing on basic science and translational research to advance diagnostics and therapeutics in medical care.

Akbarian Laboratory is exploring epigenetic regulation of gene expression in order to identify epigenetic drug targets and novel treatment avenues for psychosis, depression, and other psychiatric disease

Brennand Laboratory studies schizophrenia by reprogramming skin samples into pluripotent stem cells, later differentiated into human neurons.

Burdick Laboratory is researching neurocognitive dysfunction in major psychiatric disorders with a focus on understanding the underlying etiologies through genetics, neuroimaging, and novel treatment strategies.

Buxbaum Laboratory (Laboratory of Molecular Neuropsychiatry) is investigating human psychiatric and neurological diseases using the methods of genetics, genomics, cell and molecular biology, and animal models, with a current focus on autism, schizophrenia, and Alzheimer's disease.

Byne Laboratory (Neuroanatomy and Morphometrics Laboratory) examines the relationship between brain structure and function in health and disease, and provides anatomical assistance to a variety of other laboratories conducting postmortem molecular biological studies and in vivo neuroimaging studies in serious mental illness.

Cognitive Psychophysiology Laboratory conducts multidisciplinary research using neuroimaging and psychophysiological measures to study cognition and emotion. 

Frangou Laboratory examines the neurobiology of schizophrenia and bipolar disorders, and the effect of genetic and environmental factors, using high-field and multimodal imaging.

Gandy Laboratory is exploring the many psychiatric and neuroscientific aspects found in Alzheimer’s disease.

Gu Laboratory examines the neural and computational mechanisms underlying human beliefs, emotions, decision making, and social interaction in both health and disease, through a synthesis of neuroscience, cognitive science, and behavioral economics.

Hurd Laboratory is examining the neurobiology of underlying drug abuse and related psychiatric disorders.

Laboratory of Molecular Biology and Genetics of Neurodegeneration (Robakis Laboratory) is researching the roles and processes of molecular biology and genetic neurodegeneration in specific diseases.

Micali Laboratory is conducting psychiatry research that is related to child health and development.

Morishita Laboratory is studying the factors that help determine levels of brain plasticity and cognition in the sphere of perceptual development.

Neuropathology and Brain Banking Laboratory serves the human postmortem brain tissue needs of investigators at the Icahn School of Medicine at Mount Sinai.

Perez-Rodriguez Laboratory is investigating physiological models in psychiatry.

Pinto Laboratory is focused on identifying risk genes and biological pathways for neurodevelopmental disorders, including autism, epilepsy, schizophrenia, and Rett syndrome-like phenotypes.

Psychopharmacology Laboratory is using rodent model systems to understand behavioral, learning, and memory systems in Alzheimer’s disease.

Reichenberg Laboratory is conducting research studies in a variety of aspects of psychiatry. 

Roussos Laboratory focuses its research on the genetics of gene expressions in neuropsychiatric illnesses including schizophrenia, Alzheimer’s disease, and bipolar disorder.

Schiller Laboratory is discovering the neural mechanisms underlying emotional control and flexibility, researching neuroplasticity and behavior.

Stahl Laboratory is engaged in complex trait genetics and the inference of genetic architecture, through analysis of both common and rare variant genomic data, and through integration with other genomic and phenotypic data.