One of the important missions of PrIISM is to develop cutting-edge technology platforms. The Human Immune Monitoring Center (HIMC) provides comprehensive immune monitoring services for clinical and translational studies. In addition, the team of experts at the HIMC offers expert advice for optimal project-specific immunologic assessment and innovative approaches to evaluate immune responses in clinical studies. The Microbiome Translational Center provides centralized germ-free and gnotobiotic mouse services. It offers the Icahn School of Medicine at Mount Sinai research community access to isolators for breeding and experiments. It also provides technical support required for various germ-free and gnotobiotic experimental procedures.