Deans CoREs - Biorepository and Pathology

The Biorepository and Pathology Core at the Icahn School of Medicine at Mount Sinai provides a host of pathology services to facilitate basic, translational, and clinical research. Our mission is to build a resource of diseased and normal tissues and associated biospecimens that is readily available for new and ongoing studies across our research community.

As part of the Department of Pathology, Molecular, and Cell-Based Medicine—one of the largest pathology departments in the country—the Biorepository and Pathology CoRE has access to thousands of unique specimens and rare diagnoses. We also provide expert consultation and curation of samples to accommodate investigative needs and goals.

Currently the Biorepository supports tissue and body fluid procurement, storage, and tracking from consented and de-identified collections. Pathologists responsible for procurement can be contacted for consultation to determine investigator requirements for human specimens in translational research, and then arrange procurement as feasible.

Our basic histology services include the capability to process, embed, and section fixed and frozen tissues (both animal and human) for the Mount Sinai Health System and the external academic and biopharmaceutical community. Additional services include histochemistry, immunohistochemistry, immunofluorescence, in situ hybridization, laser capture microdissection, as well as a variety of special stains for routine light microscopic evaluation. We also offer full digital scanning capability with our quantitative and qualitative image analysis service (HALO AI), and support DNA/RNA/miRNA extraction from fluids and tissue specimens (both fixed and frozen) for downstream next generation sequencing.

Acknowledgement of CoRE in Publications, Grants, and Awards

In order to sustain the Biorepository and Pathology CoRE for current and future investigators, it is critically important to acknowledge the CoRE, as well as the clinical faculty, in all publications, grants, and awards that include any data or services derived from our facility.

This is a mandatory requirement for funding. The recommended language for acknowledgement is as follows: "This research was conducted with the support of the Biorepository and Pathology CoRE at the Icahn School of Medicine at Mount Sinai. Additionally, Dr. (name), Dr. (name), and Dr. (name) were involved in the acquisition and evaluation of tissue that was used in these studies."