As an MD/PhD student at the Icahn School of Medicine at Mount Sinai (ISMSS), you will have many opportunities to be a part of the cutting-edge research taking place in some of our nation’s best laboratories.

We are committed to training strong researchers. Our Hess Center for Science and Medicine recently added 550,000 square feet of laboratory and clinical space for further collaborations among our extensive research and physician community. Our students have been published in Proceedings of the National Academy of Sciences, Journal of Clinical Investigation, Molecular Cell, Nature, and more.

Below are some of our standout student publications from 2017.  

Bernitz JM., Daniel MG., Fstkchyan YS., and Moore K. Granulocyte colony-stimulating factor mobilizes dormant hematopoietic stem cells without proliferation in mice. Blood2017 Apr 6;129(14):1901-1912. doi: 10.1182/blood-2016-11-752923. Epub 2017 Feb 8. 

Devenyi RA, Ortega FA, Groenendaal W, Krogh-Madsen T, Christini DJ, Sobie EA. 2017. Differential roles of two delayed rectifier potassium currents in regulation of ventricular action potential duration and arrhythmia susceptibility. J Physiology. PMID: 27779762. 2017 Apr 1;595(7):2301-2317. doi: 10.1113/JP273191. Epub 2016 Dec 28.

Hamlin RE, Rahman A, Pak TR, Maringer K, Mena I, Bernal-Rubio D, Potla U, Maestre AM, Fredericks AC, Amir ED, Kasarskis A, Ramos I, Merad M, Fernandez-Sesma A. High-dimensional CyTOF analysis of dengue virus-infected human DCs reveals distinct viral signatures. JCI Insight. 2017 Jul 6;2(13). pii: 92424.

Chamaria S, Johnson K, Vengrenyuk Y, Baber U, Shameer K, Divaraniya AA, Glicksberg BS, Li L, Bhatheja S, Moreno P, Maehara A, Mehran R, Dudley JT, Narula J, Sharma SK, Kini AS.  Intracoronary Imaging, Cholesterol Efflux, and Transcriptomics after Intensive Statin Treatment in Diabetes. Sci Rep. 2017 Aug 1;7(1):7001  

Lavin, Y., Kobayashi, S., Leader, A., Amir, E.D., Elefant, N., Bigenwald, C., Remark, R., Sweeney, R., Becker, C., Levine, J.H., Meinhof, K., Chow, A., Kim-Schulze S., Wolf, A., Medaglia, C., Li, H., Rytlewski, JA., Emerson, RO., Solovyov A.,Greenbaum B.D., Sanders, C., Vignali, M., Beasley M.B., Flores, R., Gnjatic, S., Pe’er, D., Rahman, A., Amit, I., Merad, M. (2017), Innate Immune Landscape in Early Lung Adenocarcinoma by Paired Single-Cell AnalysesCell2017 May 4;169(4):750-765.e17. doi: 10.1016/j.cell.2017.04.014.

Lavin, Y, Kobayashi, S., Leader, A, Amir, E.D, Elefant, N.,  Bigenwald, C.,  Remark, R. et al. Innate Immune Landscape in Early Lung Adenocarcinoma by Paired Single-Cell AnalysesCell.  2017 May 4;169(4):750-765.e17. doi: 10.1016/j.cell.2017.04.014.

Llewellyn SR, Britton GJ, Contijoch EJ, Vennaro OH, Mortha A, Colombel JF, Grinspan A, Clemente JC, Merad M, Faith JJ. Interactions between diet and the intestinal microbiota alter intestinal permeability and colitis severity in mice. Gastroenterology. 2017 Nov 23. pii: S0016-5085(17)36388-6. [Epub ahead of print]

Menard, C., Pfau, M.L., Hodes, G.E., Kana, V., Wang, V.X., Bouchard, S., Takahashi, A., Flanigan, M.E., Aleyasin, H., LeClair, K.B., Janssen, W.G., Labonte, B., Parise E.M., Lorsch Z.S.  et al. (2017). Social stress induces neurovascular pathology promoting depression. Nat Neurosci2017 Dec;20(12):1752-1760. doi: 10.1038/s41593-017-0010-3. Epub 2017 Nov 13.

Muir J, Lorsch Z, Ramakrishnan C, Deisseroth K, Nestler EJ, Calipari ES, Bagot RC. In Vivo Fiber Photometry Reveals Signature of Future Stress Susceptibility in Nucleus Accumbens. Neuropsychopharmacology. 2018 Jan;43(2):255-263.

Mayourian J, Ceholski DK, Murphy JF, Hare JM, Sahoo S, Hajjar RJ, Costa KD. microRNA-21 as an Exosomal Mediator of Mesenchymal Stem Cell Paracrine Effects on Human Cardiac Tissue Contractility. Circ Res. 2018; in press.

Mayourian J, Ceholski DK, Gonzalez DM, Cashman TJ, Sahoo S, Hajjar RJ, Costa KD. Physiologic, Pathologic, and Therapeutic Paracrine Modulation of Cardiac Excitation-Contraction Coupling. Circ Res. 2018 Jan 5;122(1):167-183

Miller ML, Ren Y, Szutorisz H, Warren NA, Tessereau C, Egervari G, Mlodnicka A, Kapoor M, Chaarani B, Morris CV, Schumann G, Garavan H, Goate AM, Bannon MJ, IMAGEN Consortium, Halperin JM, & Hurd YL. (in press). Ventral striatal regulation of CREM mediates impulsive action and drug addiction vulnerability. Mol Psychiatry. doi: 10.1038/mp.2017.80.

Pak TR, Chacko KI, O'Donnell T, Huprikar SS, van Bakel H, Kasarskis A, Scott ER. Estimating Local Costs Associated with Clostridium difficile Infection Using Machine Learning and Electronic Medical Records. Infect Control Hosp Epidemiol. 2017 Dec;38(12):1478-1486.

Sonoshita M, Scopton AP, Ung PMU, Murray MA, Silber L, Maldonado AY, Real A, Schlessinger A, Cagan RL, Dar AC. A whole-animal platform to advance a clinical kinase inhibitor into new disease space. Nat. Chem. Biol. 2018 Jan 22 [Epub ahead of print]

Ribeiro EA*, Scarpa JR*, Garamszegi SP, Kasarskis A, Mash DC, Nestler EJ. Gene Network Dysregulation in Dorsolateral Prefrontal Cortex Neurons of Humans with Cocaine Use Disorder. Sci Rep. 2017 Jul 14;7(1):5412. 

Labonte, B., Engmann, O., Purushothaman, I., Menard, C., Wang, J., Tan, C., Scarpa, J.R., et al. (2017). Sex-specific transcriptional signatures in human depression. Nat. Med., 2017 Sep;23(9):1102-1111. doi: 10.1038/nm.4386. Epub 2017 Aug 21.  

Baum A*, Scarpa J*, Bruzelius E, Tamler R, Basu S, Faghmous J. Targeting weight loss interventions to reduce cardiovascular complications of type 2 diabetes: a machine learning-based post-hoc analysis of heterogeneous treatment effects in the Look AHEAD trial. Lancet Diabetes Endocrinol. 2017 Oct;5(10):808-815.

Wohlbold TJ, Podolsky KA, Chromikova V, Kirkpatrick E, Falconieri V, Meade P, Amanat F, Tan J, tenOever BR, Tan GS, Subramaniam S, Palese P, Krammer F. Broadly protective murine monoclonal antibodies against influenza B virus target highly conserved neuraminidase epitopes. Nat Microbiol. 2017 Oct;2(10):1415-1424