Precision Immunology Institute at Icahn School of Medicine at Mount Sinai (PrIISM)


Please go here for a full listing of all the publication from the MTC leadership team.

Highlighted Publications from the MTC

Shah, S. C., Faith, J., & Colombel, J. F. (2018). Microbial-Host Interactions in Inflammatory Bowel Disease, Functional Bowel Disease, Obesity and Obesity-Related Metabolic Disease. Gastroenterology. doi:10.1053/j.gastro.2018.06.081

Llewellyn, S. R., Britton, G. J., Contijoch, E. J., Vennaro, O. H., Mortha, A., Colombel, J. F., . . . Faith, J. J. (2018). Interactions Between Diet and the Intestinal Microbiota Alter Intestinal Permeability and Colitis Severity in Mice. Gastroenterology, 154(4), 1037-1046 e1032. doi:10.1053/j.gastro.2017.11.030

Tamburini, S., & Clemente, J. C. (2017). Gut microbiota: Neonatal gut microbiota induces lung immunity against pneumonia. Nat Rev Gastroenterol Hepatol, 14(5), 263-264. doi:10.1038/nrgastro.2017.34

Tamburini, S., Shen, N., Wu, H. C., & Clemente, J. C. (2016). The microbiome in early life: implications for health outcomes. Nat Med, 22(7), 713-722. doi:10.1038/nm.4142

Roulis, M., Bongers, G., Armaka, M., Salviano, T., He, Z., Singh, A., . . . Kollias, G. (2016). Host and microbiota interactions are critical for development of murine Crohn's-like ileitis. Mucosal Immunol, 9(3), 787-797. doi:10.1038/mi.2015.102

Dominguez-Bello, M. G., De Jesus-Laboy, K. M., Shen, N., Cox, L. M., Amir, A., Gonzalez, A., . . . Clemente, J. C. (2016). Partial restoration of the microbiota of cesarean-born infants via vaginal microbial transfer. Nat Med, 22(3), 250-253. doi:10.1038/nm.4039

Bunyavanich, S., Shen, N., Grishin, A., Wood, R., Burks, W., Dawson, P., . . . Clemente, J. C. (2016). Early-life gut microbiome composition and milk allergy resolution. J Allergy Clin Immunol, 138(4), 1122-1130. doi:10.1016/j.jaci.2016.03.041

Faith, J. J., Colombel, J. F., & Gordon, J. I. (2015). Identifying strains that contribute to complex diseases through the study of microbial inheritance. Proc Natl Acad Sci U S A, 112(3), 633-640. doi:10.1073/pnas.1418781112

Faith, J. J. (2015). Bridging the knowledge gap: from microbiome composition to function. Mol Syst Biol, 11(3), 793. doi:10.15252/msb.20156045

Clemente, J. C., Pehrsson, E. C., Blaser, M. J., Sandhu, K., Gao, Z., Wang, B., . . . Dominguez-Bello, M. G. (2015). The microbiome of uncontacted Amerindians. Sci Adv, 1(3). doi:10.1126/sciadv.1500183

Britton, G. J., & Faith, J. J. (2015). Metabolic labeling puts the microbiome under the microscope. Nat Med, 21(9), 977-978. doi:10.1038/nm.3941

Faith, J. J., Ahern, P. P., Ridaura, V. K., Cheng, J., & Gordon, J. I. (2014). Identifying gut microbe-host phenotype relationships using combinatorial communities in gnotobiotic mice. Sci Transl Med, 6(220), 220ra211. doi:10.1126/scitranslmed.3008051

Bongers, G., Pacer, M. E., Geraldino, T. H., Chen, L., He, Z., Hashimoto, D., . . . Lira, S. A. (2014). Interplay of host microbiota, genetic perturbations, and inflammation promotes local development of intestinal neoplasms in mice. J Exp Med, 211(3), 457-472. doi:10.1084/jem.20131587

Faith, J. J., Guruge, J. L., Charbonneau, M., Subramanian, S., Seedorf, H., Goodman, A. L., . . . Gordon, J. I. (2013). The long-term stability of the human gut microbiota. Science, 341(6141), 1237439. doi:10.1126/science.1237439

Clemente, J. C., Ursell, L. K., Parfrey, L. W., & Knight, R. (2012). The impact of the gut microbiota on human health: an integrative view. Cell, 148(6), 1258-1270. doi:10.1016/j.cell.2012.01.035

Bongers, G., Muniz, L. R., Pacer, M. E., Iuga, A. C., Thirunarayanan, N., Slinger, E., . . . Lira, S. A. (2012). A role for the epidermal growth factor receptor signaling in development of intestinal serrated polyps in mice and humans. Gastroenterology, 143(3), 730-740. doi:10.1053/j.gastro.2012.05.034

Faith, J. J., McNulty, N. P., Rey, F. E., & Gordon, J. I. (2011). Predicting a human gut microbiota's response to diet in gnotobiotic mice. Science, 333(6038), 101-104. doi:10.1126/science.1206025

Clemente, J. C., Jansson, J., & Valiente, G. (2011). Flexible taxonomic assignment of ambiguous sequencing reads. BMC Bioinformatics, 12, 8. doi:10.1186/1471-2105-12-8

Faith, J. J., Rey, F. E., O'Donnell, D., Karlsson, M., McNulty, N. P., Kallstrom, G., . . . Gordon, J. I. (2010). Creating and characterizing communities of human gut microbes in gnotobiotic mice. Isme j, 4(9), 1094-1098. doi:10.1038/ismej.2010.110

Clemente, J. C., Jansson, J., & Valiente, G. (2010). Accurate taxonomic assignment of short pyrosequencing reads. Pac Symp Biocomput, 3-9.

Bongers, G., Maussang, D., Muniz, L. R., Noriega, V. M., Fraile-Ramos, A., Barker, N., . . . Lira, S. A. (2010). The cytomegalovirus-encoded chemokine receptor US28 promotes intestinal neoplasia in transgenic mice. J Clin Invest, 120(11), 3969-3978. doi:10.1172/JCI42563

Faith, J. J., Driscoll, M. E., Fusaro, V. A., Cosgrove, E. J., Hayete, B., Juhn, F. S., . . . Gardner, T. S. (2008). Many Microbe Microarrays Database: uniformly normalized Affymetrix compendia with structured experimental metadata. Nucleic Acids Res, 36(Database issue), D866-870. doi:10.1093/nar/gkm815