Microscopy and Advanced Bioimaging Core

The Microscopy and Advanced Bioimaging CoRE is a shared resource facility providing access to state-of-the-art imaging equipment and analysis tools. Open to both internal and external users, it is accessible seven days a week. It houses widefield, laser scanning confocal, spinning disk confocal, multi-photon, light-sheet, and super-resolution microscopes, along with two transmission electron microscopes and a high content screener. The CoRE also houses a high-end centralized workstation for image processing, high-performance Computing (HPC) (ex: Deep Learning), and big-data storage and provides access to several commercial software programs for image analysis and data quantification.  Services offered include consultations for sample preparation, training on the microscopes, providing full imaging support, and assistance with analysis strategies. CoRE scientists can also collaborate with investigators to develop novel imaging methods and analysis approaches. The facility also provides a full service for Transmission Electron Microscopy:  tissue/cell processing, image acquisition training or assistance, and image analysis support. The Microscopy Core is an established Leica Center of Excellence, a collaboration between Icahn School of Medicine at Mount Sinai and Leica Microsystems.