Students in the Disease Mechanisms and Therapeutics training program will spend a substantial amount of time working with our investigators and dedicated to research.
| Lab Name | Description |
|---|---|
| Aggarwal Lab | Uncovering how enzymes and transcriptional and translational regulators interact with nucleic acids to affect cellular development and disease outcome |
| Akar Laboratory | Investigating arrhythmia mechanisms in structural heart disease at multiple levels of integration |
| Azeloglu Laboratory | Understanding role of mechanobiology in kidney disease using integrative experimental and computational methods |
| Bansal Laboratory | Focusing on the role of Matrix Metalloproteinase-2 in liver fibrosis and regeneration and Role of the chemokine receptors, CXCR4 and CCR5, on stellate cell biology and fibrogenesis |
| Bashir Laboratory | Researching bioinformatics/computational biology topics, primarily on problems related to genomic architecture |
| Blitzer Laboratory | Studying cellular mechanisms giving rise to stable forms of synaptic plasticity in the brain, especially signaling pathways that regulate protein synthesis following synaptic stimulation |
| Campbell Laboratory | Utilizing cell-based assays and rodent models to identify and characterize key mediators of glomerular disease progression |
| Chaudhry Laboratory | Focusing on cell cycle regulation of cardiomyocytes and endogenous progenitor cells in the heart |
| Benjamin Chen Laboratory | Investigating the biology of HIV assembly and viral infection through virological synapses |
| Shu-Hsia Chen Laboratory | Exploring the activation of innate and adaptive immunity |
| John Cijiang He Research | Studying the role of HIPK2 in kidney fibrosis |
| Costa Laboratory | Focusing on cell cycle regulation of cardiomyocytes and endogenous progenitor cells in the heart |
| Dar Laboratory | Exploring links between the regulation of drug targets and the system level properties of biological networks within cells and animals |
| DeVita Research Group | Focused on drug discovery to meet the needs of patients for whom there are limited therapeutic options |
| Devi Laboratory | Exploring the molecular mechanisms and functional implications of opioid receptor dimerization, and focusing on drug discovery to meet the needs of patients who have limited therapeutic options |
| Evan Flatow Research | Conducting research in biomechanics/bioengineering, signal transduction, tendon biology, and tendon disease |
| Filizola Laboratory | Engaging in computer-aided structural bio and drug design |
| Friedman Laboratory of Liver Research | Researching the role of KLF6 in cell growth and human cancer, as well as molecular regulation of hepatic fibrosis |
| Gelb Research Group | Focusing on disease gene discovery using genomic techniques and characterization of the biological roles of such genes in disease pathogenesis |
| Han Laboratory | Identifying neurophysiological basis of susceptibility and resilience to chronic stress at molecular (ion channel and receptor) and cellular levels |
| Iyengar Laboratory | Exploring how signals are routed and processed through cellular signaling networks, including information sorting and integration mechanisms |
| Jin Laboratory | Discovering chemical probes for histone methyltransferases (HMTs) and creating functionally selective ligands of G protein-coupled receptors |
| Kenny Laboratory | Researching applications in behavioral and molecular neuroscience |
| Lebeche Laboratory | Targeting molecular and cellular pathways to improve contractile function and survival in failing cardiac myocytes |
| Ma’ayan Laboratory | Applying computational and mathematical methods to study the complexity of regulatory networks in mammalian cells |
| Maze Laboratory | Exploring the role of chromatin dynamics, nucleosomal turnover, and histone variant exchange in the central nervous system during periods of transcriptional, synaptic, and behavioral plasticity |
| Garcia-Ocana Research – Diabetes, Obesity and Metabolism Institute (DOMI) | Focusing on tissue regeneration, growth factors, and intracellular signaling |
| Orthopedics Research Laboratory | Using multidisciplinary approaches to address fundamental questions in the field of orthopaedic research |
| Roman Osman Research | Studying proteolysis by integral membrane proteins,and blocking antigen presentation in autoimmunity and targeting MAGE inhibition of apoptosis |
| Palese Laboratory | Focusing on fundamental questions concerning the genetic make-up and biology of viruses, as well as virus-host interactions |
| Parekh Laboratory | Working to decipher the interplay between PDEs and synaptic responsiveness |
| Paisan-Ruiz Laboratory | Studying Mantle Cell Lymphoma (MCL), a rare and usually fatal subtype of non-Hodgkin’s lymphoma, in collaboration with a Phase II clinical trial at the NIH |
| Parsons Laboratory | Identifying the underpinnings of cancer and to using this information to improve prevention and treatment |
| Reddy Laboratory | Studying genes that control cell homeostasis and how these controls are dysregulated during the neoplastic process |
| Lisa Satlin Research | Defining the mechanisms leading to the acquisition, maintenance and regulation of transepithelial transport in the mammalian cortical collecting duct |
| Schaniel Laboratory | Researching integrated stem cell biology; genomics; regenerative biology; and pharmacology Reprogramming, disease modeling and therapeutics with pluripotent stem cells |
| Schlessinger Laboratory | Developing and applying novel computational approaches and collaboratively characterizing proteins that may be pharmacologically important in future cancer therapies |
| Donald Scott Research - Diabetes, Obesity and Metabolism Institute (DOMI) | Working on the nutritional regulation of cellular phenotype |
| Sealfon Laboratory | Using diverse systems biology approaches to study and model the mechanisms of cellular decoding of extracellular stimuli |
| Sobie Laboratory | Increasing a fundamental understanding of how calcium signaling in heart cells interacts with and influences the heart’s electrical and mechanical functions |
| Andrew Stewart Research | Striving to understand and develop novel means for inducing the replication and regeneration of insulin-producing pancreatic beta cells |
| Vasavada Laboratory - Diabetes, Obesity and Metabolism Institute (DOMI) | Researching the pathways and mechanisms that regulate beta cell growth, survival and function, with the ultimate objective being to enhance regeneration of functional beta cells in vivo |
| Martin Walsh Research | Investigating applications in structural and chemical biology, genetic and genomic sciences |
| Yue Laboratory | Delving into the molecular and cellular mechanisms of neurodegeneration that causes human |