Laboratories

As a student in our Neuroscience Graduate Training Program, you will devote a significant portion of your time to research. Explore our labs and meet our investigators.

Lab Name Description
Ahfeldt Laboratory Neurodegenerative Disease Modeling
Akbarian Laboratory Laboratory of epigenetic regulation of the human brain
Balchandani Laboratory The ANRP is focused on facilitating the most innovative brain imaging research, while leveraging the technical and clinical advantages of the Icahn School of Medicine at Mount Sinai (ISMMS)
Baxter Laboratory Using animal models to establish causal links between manipulations of defined neural circuits, behavioral and cognitive functions
Benson Laboratory Investigating mechanisms required to generate normal functioning neural circuits
Blanchard Laboratory Genetic and Environmental Vulnerability to Neurodegeneration.
Blenkinsop Laboratory Our laboratory works to understand the basic biology of the adult human eye in an effort to reveal mechanisms for regeneration.
Blitzer Laboratory Regulation of translation in long-term potentiation
Breen Laboratory Large-scale functional genomics to study gene expression and RNA editing in brain development and neurodevelopmental disorders
Buettner Laboratory Researching glucose and lipid metabolism in liver and adipose tissue
Buxbaum Laboratory The laboratory of Molecular Neuropsychiatry studies human psychiatric and neurological diseases using the methods of genetics, genomics, cell and molecular biology and animal models. Current laboratory focus includes autism, schizophrenia and Alzheimer's disease.
Cai (Denise) Laboratory Temporal Dynamics of Learning and Memory
Cai (Dongming) Laboratory Dongming Cai is a neurologist and neuroscientist working in key research areas for studies in aging and neurodegenerative disorders. A major focus of her work is investigating the molecular and cellular mechanisms underlying Alzheimer’s disease (AD) pathogenesis, with the goal of developing novel therapeutic strategies for AD and other neurodegenerative diseases
Castellano Laboratory Mechanisms of Neuroimmunology, Neurodegeneration, and systemic-CNS interactions
Charney (Alex) Laboratory The Brain and Data Sciences Lab is known for using multiple types of genomic data to dissect the clinical features of schizophrenia and bipolar disorder, developing a novel framework for human brain research with the Living Brain Project
Charney Laboratory  
Chen Laboratory Exploring the use of clinical genome informatics
Chess Laboratory Studying unusual mechanisms involved in regulating gene expression
Clark Laboratory Neuropsychology & Neuroimaging
Clem Laboratory Using molecular and electrophysiological approaches, including optogenetic stimulation, to identify impact of associative fear conditioning on neural pathways and neurons in limbic and cortical regions
Crary Laboratory Our research focuses on the molecular neuropathology of neurodegenerative diseases
Cropper Laboratory Studying neural mechanisms of sensorimotor integration
Dams-O’Connor Laboratory The Brain Injury Research Center of Mount Sinai (BIRC-MS) investigates cutting-edge solutions for improving both health and quality of life following traumatic brain injury (TBI)
De Araujo Laboratory Body-Brain Communication: Information flow between the body and the central nervous system
De Rubeis Laboratory Understanding the developmental defects resulting from disruptive mutations in novel high-risk genes identified from our ongoing large-scale genomic studies in autism (ASD) and intellectual disability (ID)
Devi Laboratory Researching molecular mechanisms in neurology
Dracheva Laboratory We study cell-type-specific epigenetic regulation in the human brain in brain disorders, development, and evolution
Dudley Laboratory Focusing on translational and biomedical informatics approaches to address critical challenges in systems medicine
Ehrlich Laboratory  
Elder Laboratory Research interests include Alzheimer's disease and related dementias, in particular how mutations in presenilin-1 cause familial Alzheimer's disease using transgenic mouse models. We also study the normal biological functions of the presenilin-1 gene using mouse models and cell culture.
Ellis-Davies Laboratory Exploring optical methods and neurophysiology
Foss-Feig Laboratory Using multimodal neuroimaging (EEG, MRI), psychophysical testing, eye tracking, and targeted clinical assessments, our research investigates sensory and perceptual processing as they differ between autism spectrum disorder (ASD) and typical development.
Friedel Laboratory Brain tumors remain a deadly form of cancer. Our research goal is to provide a better understanding of the molecular machinery that drives proliferation, invasiveness, and therapy resistance of brain tumor cells.
Fromer Laboratory  
Gama-sosa Laboratory  
Gandy Laboratory Dr. Gandy is an international expert in the metabolism of the sticky substance called amyloid that clogs the brain in patients with Alzheimer's.
Goate Laboratory Focusing on dementia (Alzheimer's and frontotemporal) and addiction (alcohol)
Goldstein Laboratory Rita Goldstein and Nelly Alia-Klein direct the NARC (Neuropsychoimaging of Addiction and Related Conditions) research group that uses multimodality functional neuroimaging methods to explore the neurobiological basis of impaired cognitive and emotional functioning in human drug addiction and other disorders of self-control
Goosens Laboratory The Laboratory for Biological Systems in Stress and Disease studies the systems-level biology of emotional memory and stress in healthy rodents and humans, and examines dysregulation of this biology in animal models of psychiatric disease and human patient populations.
Gu Laboratory Computational Psychiatry Unit
Haghighi Laboratory Investigating epigenetic changes in disease and normal human postmortem brain samples, providing a snapshot of potential abnormalities
Harony-Nicolas Laboratory Our lab is focused on understating the mechanisms underlying social behavior deficits in autism spectrum disorder (ASD) and the implication of the hypothalamic oxytocin system in ASD and other neurodevelopmental disorders.
Haroutunian Laboratory Single cell and bulk gene and protein expression in the human brain; neurobiology and neuropathology of successful aging, Alzheimer’s disease and schizophrenia
Hambardzumyan Laboratory Investigate the role of myeloid cells in how they contribute to pediatric and adult glioblastoma growth and response to therapy
Hazlett Laboratory Our team conducts multidisciplinary and translational research utilizing neuroimaging (e.g., fMRI) and other psychophysiological measures (e.g., startle eyeblink modulation) to improve our understanding of the neurobiological basis of normal and disordered cognition and emotion
Hedden Laboratory Aging and Neurodegenerative Disease
Hof Laboratory Conducting neuromorphology research
Holstein Laboratory Researching chronic liver disease through genomics; clinical diagnostics; chemical biology; biostatistics; and informatics
Horng Laboratory Understanding the mechanisms by which CNS barrier cells regulate immune cell activation and entry during this infiltrative process may identify novel therapeutic strategies for MS and other CNS autoimmune diseases
Huckins Laboratory Analytical Genomics of Vulnerable Populations
Huntley Laboratory Researching synaptic circuit development and neural plasticity
Hurd Laboratory Studying the neurobiology of underlying drug abuse and related psychiatric dysfunction
Iatridis Laboratory Developing minimally invasive interventions to prevent and repair painful spinal pathologies with a focus on intervertebral disc (IVD) degeneration.
Iyengar Laboratory Exploring how signals are routed and processed through cellular signaling networks, including information sorting and integration mechanisms
Janecka Laboratory Understanding the etiological contribution of the environment to neurodevelopmental disorders, leveraging observational, genetic and epigenetic epidemiology
Jen Laboratory  
Kasarskis Laboratory Dr. Kasarskis leads collaborative projects aimed at new therapeutics and diagnostics, and his research focuses on developing and applying technology to several areas including pathogen surveillance, pharmacogenomics, and the genetics of sleep.
Kenny Laboratory Analyzing human genetic variation to address fundamental questions in biology, medicine, and anthropology
Kimhy Laboratory Experimental Psychopathology Laboratory
Kiraly Laboratory Utilizes translationally-relevant animal models and samples from patient populations to investigate the role of the immune system and the gut microbiome in the pathophysiology of mental illness
Koenigsberg Laboratory Dr. Koenigsberg has had a longstanding research and clinical interest in borderline personality disorder (BPD). He is currently studying the emotional instability characteristic of borderline personality disorder.
Nash Family Center for Advanced Circuit Therapeutics (C-ACT ) To advance precision neurosurgical treatments for complex neuropsychiatric disorders through the rapid translation of neuroscience and neuroengineering innovations
Maze Laboratory Chromatin regulatory mechanisms of neural plasticity and disease
McAlpine Laboratory We take a multidisciplinary approach investigating the immune system in sleep, cardiovascular disease and Alzheimer’s disease
Mlodzik Laboratory The main focus of our lab is the study of Wnt/Frizzled-planar cell polarity (PCP) signaling and associated regulatory and signaling specificity mechanisms
Mobbs Laboratory Researching the role of aging in obesity, diabetes, and Alzheimer's 
Montgomery Laboratory Dr. Montgomery’s research focuses on developing, testing and disseminating psychological and integrative interventions to reduce suffering related to cancer and its treatment.
Moore Laboratory  
Morgello Laboratory Dr. Morgello is the principal investigator of a large, multidisciplinary cohort study/ research resource; examining neurologic, neuropsychologic, psychiatric, neuropathologic, and general medicine abnormalities in HIV.
Morishita Laboratory Cortical Mechanisms of Perceptual, Cognitive & Social Development
Morris Laboratory Studying developmental brain plasticity and cognition
Nael Laboratory Kambiz Nael, MD
Neuropsychoimaging of Addiction and Related Conditions (NARC) Rita Goldstein and Nelly Alia-Klein direct the NARC (Neuropsychoimaging of Addiction and Related Conditions) research group that uses multimodality functional neuroimaging methods to explore the neurobiological basis of impaired cognitive and emotional functioning in human drug addiction and other disorders of self-control
Nestler Laboratory Studying molecular mechanisms of addiction and depression
Paisan-Ruiz Laboratory Dr. Paisan-Ruiz’s laboratory focuses on elucidating and understanding the molecular basis underlying and contributing to movement disorders such as Parkinson's disease (PD), parkinsonian-like syndromes, and essential tremor (ET).
Parvaz Laboratory Research in the Motivational and Affective Psychopathology Laboratory (MAPlab) focuses on neuroimaging, psychophysiological and computational phenotyping to study motivational, social and affective processes in neuropsychiatric disorders
Pasinetti Laboratory Studying biology and treatment of destructive inflammatory mechanisms in the brain, often related to neurodegenerative disorders
Pinto Laboratory Identifying genes and biological pathways involved in various neurodevelopmental disorders
Pereira Laboratory Pereira Lab studies the neurobiology of the Aging Brain and Alzheimer’s disease (AD). It investigates the susceptibility of glutamatergic neural circuits to tau pathology, synaptic and neuronal loss, mechanisms of tau propagation and neuronal susceptibility to AD, intermittent hypoxia in AD, apolipoprotein E mechanisms and potential novel therapeutic approaches in AD using a translational approach
Plevan Laboratory The Plevan laboratory  research interests center around the neurobiology and the neurochemistry of several psychiatric conditions including suicide and drug addiction.
Rajbhandari Laboratory Brain, Vagus and Body Mechanisms of Fear and Stress
Rajan Laboratory Brain Research and Artificial Intelligence
Raj Laboratory Research in our laboratory focuses on mechanisms underlying the regulation of gene expression and how these mechanisms are disrupted in neurodegenerative diseases.
Rich Laboratory Neurophysiology of Affect and Cognition
Robakis Laboratory Laboratory of Molecular Biology and Genetics of Neurodegeneration
Roussos Laboratory Panos Roussos's research is focused on discerning the neurobiology of neuropsychiatric illnesses through understanding the regulation of gene expression.
Rudebeck Laboratory Exploring interactions between the prefrontal cortex and subcortical structures, related to emotional regulation and decision making
Russo Laboratory Researching neuroplasticity and behavior
Saez Laboratory In decision-making behavior, a major focus of our research, these include prefrontal cortical areas, dopaminergic and serotonergic systems
Salton Laboratory Investigating how neurotrophic growth factors, including nerve growth and brain-derived neurotrophic factors, regulate nervous system development and function
Schadt Laboratory Dr. Schadt is an expert on the generation and integration of very large-scale sequence variation, molecular profiling and clinical data in disease populations for constructing molecular networks that define disease states and link molecular biology to physiology.
Schaefer Laboratory Identifying the epigenetic basis of neurodegenerative and psychiatric disorders
Schiller Laboratory Discovering neural mechanisms underlying emotion and social cognition in the human brain
Sealfon Laboratory Using diverse systems biology approaches to study and model the mechanisms of cellular decoding of extracellular stimuli
Shen Laboratory Performing statistical and integrated analysis of molecular mechanisms of drug addiction and depression
Shuman Laboratory Our primary goal is to find causal circuit mechanisms that lead to seizures and cognitive deficits in epilepsy and determine how they can be suppressed with novel interventions.
Silverman Laboratory Silverman Laboratory is focused on characterizing phenotypes and endophenotypes in schizophrenia, dementia, successful aging, and autism for use in molecular genetic studies.
Slesinger Laboratory Focusing on the function of neural circuits in both normal and diseased states
Sokol Laboratory Exploring various processes in epithelial cells; stem cells; migrating cells; asymmetric division; growth factors; and mechanotransduction
Soriano Laboratory Exploring the growth factor signaling pathways that have important roles in mouse embryonic development
Stanley Laboratory  
Swirski Laboratory Our research is directed towards understanding how leukocytes connect lifestyle stressors with various organ systems including metabolism, the endocrine and nervous systems, and physiology as a whole
Tang Laboratory  
Tankou Laboratory Laboratory of the Gut Brain Axis in CNS Autoimmunity
Varga Laboratory Mechanisms of learning and memory and the role of sleep in memory consolidation
Velthorst Laboratory Our laboratory incorporates psychological, epidemiological and biological approaches to better understand risk for, and functional trajectories of schizophrenia and related neurodevelopmental disorders
Wang Laboratory Utilizing biological mass spectrometry to probe protein interactions and processing mechanisms of amyloid beta-protein in Alzheimer's disease
Weiss Laboratory Combining behavioral, morphological, electrophysiological, cell biological and molecular-biological techniques
Wright Laboratory Measures human environment comprehensively including chemicals, air pollution, social stressor and nutrition
Wu Laboratory Laboratory of Neural Systems, Structures and Genetics
Xu Laboratory Our research is directed at better understanding how the network of transcription factors/chromatin regulators and gene interactions drive progenitor cell development, maintenance, and regeneration in the inner ear and kidney
Yakushin Laboratory  
Yang Laboratory Our lab focuses on the understanding of genetic and epigenetic programs that control the development of distinct cell types
Yehuda Laboratory Our programs are designed to gain a better scientific understanding of the biology of stress reactions, and how to treat them better.
Yue Laboratory Studying molecular and cellular mechanisms of neurodegeneration that cause human neurological disorders such as Parkinson’s, Huntington’s and Alzheimer’s diseases
Zachariou Laboratory Using advanced genetic mouse models, viral mediated gene transfer and optogenetics, to understand network and cell-type mechanisms underlying chronic pain, addiction, and depression
Zhang Laboratory Focusing on construction and characterization of multiscale biological networks, from large-scale genomic, genetic, epigenetic, proteomic and clinical data
Zou Laboratory Researching molecular mechanisms of neuronal birth, extend axons, regeneration or failure to regenerate after mammalian CNS injury

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Application Deadline
December 1